Key Ingredients

Saccharomyces boulardii

A hardy probiotic yeast that balances gut flora to effectively manage diarrhea and loose stools.

Bromelain

Natural pineapple enzyme that breaks down proteins to maximize nutrient absorption from meat.

MOS

A yeast-derived prebiotic that prevents harmful bacteria from sticking to the gut lining and boosts immune health.

Lipase

Specialized fat-digesting enzyme that supports the pancreas and prevents issues from fatty diets.

FOS

FOS serves as 'food' for probiotics like Saccharomyces boulardii, helping them grow and multiply

Amylase

  • Boosts starch and carbohydrate digestion to ensure smoother and more efficient energy conversion.

Fast Stool Support

When your dog’s digestion feels off, PAWDFENDER’s Saccharomyces boulardii helps gently firm loose stools and restore a regular digestive rhythm. With the addition of amylase, protease, and lipase, it also helps relieve digestive pressure naturally.
*Studies suggest Saccharomyces boulardii may help reduce the duration of diarrhea.*¹

Supports Gut Balance & Beneficial Bacteria

Not all probiotics are created equal.
PAWDFENDER’s formula combines Saccharomyces boulardii with prebiotics FOS and MOS, nourishing beneficial bacteria and supporting a healthier gut microbiome.
*Research indicates support for microbiota balance and reduction of harmful bacteria.*²

Reliable During Antibiotics & Stress

Times of change—like antibiotics, travel, or diet shifts—can disrupt a dog’s gut.
PAWDFENDER Saccharomyces boulardii has been shown to remain active during these sensitive periods, helping maintain digestive stability and reduce the risk of antibiotic-associated diarrhea.
*Clinical studies in dogs show Saccharomyces boulardii supplementation helps prevent diarrhea during antibiotic use.*³

Noticeable Results in About a Week

Small improvements can make a big difference.
With consistent use, many pet parents notice more regular stools and a calmer digestive system within about a week.
*Clinical studies in dogs show Saccharomyces boulardii can improve stool consistency and digestive regularity.*⁴

Long-Term Gut Resilience

A balanced gut is more than short-term relief — it’s about ongoing stability and recovery. *Saccharomyces boulardii has been shown to help restore microbial balance after digestive disruption and reduce stress‑linked gut markers in dogs.*⁵

Everything You Need to Know About Saccharomyces Boulardii

Frequently Asked Questions

PawDefender combines Saccharomyces boulardii with FOS, MOS and digestive enzymes for daily digestive support in dogs and cats.

Each 1 g sachet contains 2.5 billion CFU of Saccharomyces boulardii. Feed one sachet per pet daily by mixing it into their usual food. Each box provides 30 daily servings for one pet.

Research note

A small study in dogs with chronic enteropathies reported improved stool consistency and frequency when Saccharomyces boulardii was added to standard treatment, compared with placebo.

This study evaluated dogs, not cats, and did not test PawDefender's finished formula.
D'Angelo et al. Double-blinded, placebo-controlled study of Saccharomyces boulardii in dogs with chronic enteropathies.

Saccharomyces boulardii has been studied during antibiotic use in dogs. A small experimental study reported reduced lincomycin-associated diarrhea under the study conditions. A separate laboratory canine gut model study investigated microbiota recovery after antibiotic disturbance.

These studies did not evaluate PawDefender's finished formula and do not establish the same outcomes in cats.

Aktaş et al. (2007). Efficacy of Saccharomyces boulardii as a probiotic in dogs with lincomycin-induced diarrhoea.

Deschamps et al. (2025). Antibiotic disturbance and microbiota recovery in a laboratory canine gut model.

Each 1 g sachet contains:

• Saccharomyces boulardii: 2.5 billion CFU
• FOS: 150 mg
• MOS: 150 mg
• Bromelain: 30 mg
• Lipase: 20 mg
• Amylase: 100 mg

Saccharomyces boulardii is a probiotic yeast. FOS and MOS are included as prebiotics, while bromelain, lipase and amylase are digestive enzymes.

The inactive ingredient is maltodextrin. The suggested serving for dogs and cats is one sachet daily

PawDefender is formulated for daily digestive support in dogs and cats. The suggested serving is one 1 g sachet per pet daily.

For ongoing use, ask your veterinarian whether this formula is appropriate for your pet, especially if they are very young, have a medical condition or take medication. Suitability depends on the individual pet; no supplement can be guaranteed free of side effects.

A yeast probiotic contains a probiotic yeast rather than probiotic bacteria. Saccharomyces boulardii is the yeast probiotic used in PawDefender's formula.

PawDefender combines it with FOS, MOS and digestive enzymes in individual powder sachets for dogs and cats. Yeast-based and bacterial probiotic products differ in their ingredients and concentrations, so they should not be treated as interchangeable.

There is no guaranteed response time. Changes depend on your pet's diet, health and the cause of their digestive symptoms. Monitor their stool, appetite and usual behavior. Contact your veterinarian if symptoms continue or worsen rather than waiting for a promised deadline.

Yes. Gentle, non-irritating formula with digestive enzymes and prebiotics. Even dogs with sensitive digestion or picky eating can safely benefit.

For this PawDefender formula, give one 1 g sachet per pet daily. Mix the powder into your dog's or cat's usual wet or dry food.

Each sachet contains 2.5 billion CFU of Saccharomyces boulardii. One box contains 30 sachets, providing 30 daily servings for one pet.

These directions apply to this product. Other Saccharomyces boulardii supplements may have different concentrations and feeding instructions.

Yes. Saccharomyces boulardii helps regulate digestion, supports gut-immune signaling, reduces inflammation, and promotes overall well-being. Long-term use builds gut resilience.

Reference: Meineri et al., 2022. Effects of Saccharomyces boulardii on immune biomarkers in dogs

https://pubmed.ncbi.nlm.nih.gov/36006304/

A yeast probiotic contains a probiotic yeast rather than probiotic bacteria. Saccharomyces boulardii is the yeast probiotic used in PawDefender's formula.

PawDefender combines it with FOS, MOS and digestive enzymes in individual powder sachets for dogs and cats.

Yeast-based and bacterial probiotic products differ in their ingredients and concentrations, so they should not be treated as interchangeable. Ask your veterinarian which formula is appropriate for your pet.


Your Health in Trusted Hands!

Real Stories, Real Results

“What surprised me the most was how quickly this product worked. Our dog used to have soft stools and occasional diarrhea. After giving this Saccharomyces boulardii for just three days, his stools became very healthy and well-formed. It really is an excellent probiotic product.”

- sherly .D

“I’ve tried several probiotics for my dog before, but this Saccharomyces boulardii supplement has worked the best. My dog used to have occasional digestive issues and loose stools, and after adding this to his routine, I noticed a clear improvement in just a few days. His digestion seems much more stable now, and his stools are firm and healthy. It’s easy to give and my dog takes it without any problems. I’m really happy with the results and would definitely recommend it to other dog owners looking for digestive support.“

- Jane M.
  • Scientifically Formulated

    Empowered by nature, backed by science, and committed to uncompromising quality and efficacy

  • Vet Recommended

    Trusted by experts, formulated with care,to ensure the gold standard in pet nutrition

  • Non-GMO

    We carefully evaluate every ingredient, ensuring they are non-GMO.

  • natural ingredients

    Gentle plant-based actives that work in harmony with your dog's system for safe and effective support

  • Third-party tested

    We hold ourselves and our ingredients to the highest standards.

  • No heavy metals

    We guarantee the highest purity, ensuring our products are free from heavy metals.


References

McFarland LV. Systematic review and meta-analysis of Saccharomyces boulardii in diarrhea treatment.

Kelesidis T, Pothoulakis C. Efficacy and safety of Saccharomyces boulardii for gastrointestinal disorders.

Herstad KMV et al. Saccharomyces boulardii supplementation prevents antibiotic-associated diarrhea in dogs.

Herstad KMV et al. Effects of Saccharomyces boulardii supplementation on stool quality in dogs with acute diarrhea.

IDeschamps C, et al. Live Saccharomyces boulardii restores gut microbiota after antibiotic disturbance in canine gut model.

Meineri G, et al. Effects of Saccharomyces boulardii supplementation on fecal parameters and stress markers in adult dogs.